| Customization: | Available |
|---|---|
| Shape: | Liquid |
| Product Model: | 0.5mg |
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Composition: Selamectin and Sarolaner
Appearance: Colorless to yellow transparent liquid.
Pharmacological effect:
Pharmacodynamics: Selamectin is a semi-synthetic compound of avermectins, which can make parasite neurons long-lasting superpolar by activating and/or enhancing glutamate-mediated chloride channel (GluCl) in invertebrates changes, disrupting its normal neurotransmission, resulting in paralysis, death or expulsion of the worm.
Sarolaner is an isoxazoline compound, mainly by blocking the γ-aminobutyric acid-mediated chloride ion channel (GABACl) in the central nervous system of insects and acarids, so as to prevent the influx of chloride ions, and nerve stimulation triggers nerve excitation increase, resulting in the death of the parasite.
Selamectin and Sarolaner have different mechanisms of action on GluCl and GABACl respectively, but the two will not interfere pharmacologically, selamectin exerts a functional blocking effect, and sarollana exerts a channel activity blocking effect , and synergistically destroy the nerve and muscle tissue functions of invertebrates, making the anthelmintic activity enhanced. Therefore, this product has a broad-spectrum anthelmintic effect, and can prevent and control internal and external parasites in cats.
Pharmacokinetics: The mean bioavailability of selamectin and Sarolaner are 40.5% and 57.9%, respectively, and can be distributed systemically. Selamectin and Sarolaner have long half-lives in cats, 12.5 days and 41.5 days, respectively. In cats, selamectin is mainly eliminated in the feces as the original form, and salolana is mainly eliminated in the unchanged form through the bile and feces.
Indication:
Ø For the treatment and prevention of cat flea infection, auxiliary treatment of allergic dermatitis caused by fleas;
Ø Treating tick, ear mite, and lice infestation in cats;
Ø Treat feline roundworm and hookworm infections;
Ø Prevent feline heartworm disease.
Usage and dosage:
Cats 8 weeks of age and above, weighing 1.25kg and above.
Calculated by Selamectin and Sarolaner. External application: one dose, per 1kg of body weight, for cats, 6mg of selamectin and 1mg of sarolaner, administered once a month.
| Cat weight (kg) | Specifications and dosage | ||
| 0.25 mg | 0.5 mg | 1 mg | |
| 1.25 ≤ Weight ≤2.5 | 1 tablet | ||
| 2.5 < weight ≤ 5 | 1 tablet | ||
| 5 < weight ≤ 10 | 1 tablet | ||
| Weight > 50 | Select the right combination of specifications for administration | ||
Adverse reactions:
1. This product may cause mild and temporary itching at the medication site.
2. In a few cases, this product may cause mild to moderate hair loss, erythema and animal salivation at the medication site.
Shelf life: 2 years.
Specification:
(1)0.25ml: 15mg+2.5mg (2)0.5ml: 30mg+5mg (3)1.0ml: 60mg+10mg
Packaging:50 tablets/bottle
Storage:Sealed and stored in a dry place below 30C.
Lucpets (Jinan) is dedicated to animal healthcare, focusing on the R&D, manufacture and promotion of pet food and health products, diagnostic reagents and animal medicines. Our mission is to be the health guardian of your animal companion.
The company has a professional R&D team, provides creative solutions and is committed to meeting the highest requirements of customers. Equipped with a R&D team of 4 PhDs, 4 masters and several undergraduates, the company has rich experience in product development. The laboratory is equipped with high-performance liquid chromatography(HPLC), gas chromatography (GC), drug stability comprehensive test box and other equipment to ensure the efficient development of new products.
The company has three production bases, covering the production of animal food, health products, animal drugs and raw materials. It is equipped with modern production workshops and fully automatic production systems and has established a strict and standardized quality control mechanism along with a quality assurance system to ensure high quality and stable production of products.
We have always paid attention to sustainable development. While the company is growing rapidly, we have always paid attention to environmental protection, employee health protection and fulfilled our social responsibilities.
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